1BWK

OLD YELLOW ENZYME (OYE1) MUTANT H191N

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003959	molecular_function	NADPH dehydrogenase activity
A	0005829	cellular_component	cytosol
A	0010181	molecular_function	FMN binding
A	0016491	molecular_function	oxidoreductase activity
A	0018548	molecular_function	pentaerythritol trinitrate reductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE FMN A 401

Chain	Residue
A	PRO34
A	GLY324
A	ASN325
A	GLY347
A	ARG348
A	PHE374
A	TYR375
A	HOH536
A	HOH540
A	HOH615
A	PRO35
A	LEU36
A	THR37
A	GLY72
A	GLN114
A	ASN191
A	ASN194
A	ARG243

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000305|PubMed:9830020

Chain	Residue	Details
A	LEU197

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:11668181, ECO:0000269|PubMed:7881908, ECO:0000269|PubMed:9830019

Chain	Residue	Details
A	ARG38
A	LEU115
A	LEU244
A	PHE349

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site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:11668181, ECO:0000269|PubMed:7881908

Chain	Residue	Details
A	SER192
A	GLY195
A	GLN376

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	5
Details	M-CSA 319

Chain	Residue	Details
A	ARG38	electrostatic stabiliser, hydrogen bond donor
A	SER192	electrostatic stabiliser, hydrogen bond donor
A	GLY195	electrostatic stabiliser, hydrogen bond donor
A	LEU197	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
A	SER252	hydrogen bond donor, increase acidity

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