1BWD
INOSAMINE-PHOSPHATE AMIDINOTRANSFERASE STRB1 FROM STREPTOMYCES GRISEUS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006601 | biological_process | creatine biosynthetic process |
| A | 0015067 | molecular_function | amidinotransferase activity |
| A | 0015068 | molecular_function | glycine amidinotransferase activity |
| A | 0015069 | molecular_function | scyllo-inosamine-4-phosphate amidinotransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0017000 | biological_process | antibiotic biosynthetic process |
| A | 0019872 | biological_process | streptomycin biosynthetic process |
| B | 0006601 | biological_process | creatine biosynthetic process |
| B | 0015067 | molecular_function | amidinotransferase activity |
| B | 0015068 | molecular_function | glycine amidinotransferase activity |
| B | 0015069 | molecular_function | scyllo-inosamine-4-phosphate amidinotransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0017000 | biological_process | antibiotic biosynthetic process |
| B | 0019872 | biological_process | streptomycin biosynthetic process |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Amidino-cysteine intermediate"} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 7 |
| Details | a catalytic site defined by CSA, PubMed 9922132 |
| Chain | Residue | Details |
| A | ASP179 | |
| A | ASP229 | |
| A | HIS331 | |
| A | ARG127 | |
| A | CYS332 | |
| A | ASP108 | |
| A | HIS227 |
| site_id | CSA2 |
| Number of Residues | 7 |
| Details | a catalytic site defined by CSA, PubMed 9922132 |
| Chain | Residue | Details |
| B | ASP179 | |
| B | ASP229 | |
| B | HIS331 | |
| B | ARG127 | |
| B | CYS332 | |
| B | ASP108 | |
| B | HIS227 |
| site_id | MCSA1 |
| Number of Residues | 8 |
| Details | M-CSA 434 |
| Chain | Residue | Details |
| A | GLU9 | modifies pKa |
| A | ASP108 | electrostatic stabiliser |
| A | ASP179 | modifies pKa |
| A | HIS227 | proton shuttle (general acid/base) |
| A | ASP229 | proton shuttle (general acid/base) |
| A | ASN286 | modifies pKa |
| A | HIS331 | proton shuttle (general acid/base) |
| A | CYS332 | covalent catalysis, proton shuttle (general acid/base) |
| site_id | MCSA2 |
| Number of Residues | 8 |
| Details | M-CSA 434 |
| Chain | Residue | Details |
| B | GLU9 | modifies pKa |
| B | ASP108 | electrostatic stabiliser |
| B | ASP179 | modifies pKa |
| B | HIS227 | proton shuttle (general acid/base) |
| B | ASP229 | proton shuttle (general acid/base) |
| B | ASN286 | modifies pKa |
| B | HIS331 | proton shuttle (general acid/base) |
| B | CYS332 | covalent catalysis, proton shuttle (general acid/base) |
