1BTG

CRYSTAL STRUCTURE OF BETA NERVE GROWTH FACTOR AT 2.5 A RESOLUTION IN C2 SPACE GROUP WITH ZN IONS BOUND

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005102	molecular_function	signaling receptor binding
B	0005102	molecular_function	signaling receptor binding
C	0005102	molecular_function	signaling receptor binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN C 900

Chain	Residue
C	HOH958
C	HOH959
C	HIS84
C	ASP105
C	ZN901

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN C 901

Chain	Residue
A	GLU94
C	ASP105
C	ZN900
C	HOH959
C	HOH960

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 902

Chain	Residue
B	HIS84
B	ASP105
B	HOH961
B	HOH962

---

site_id	ZN1
Number of Residues	2
Details

Chain	Residue
C	VAL48
C	ASP105

---

site_id	ZN2
Number of Residues	2
Details	ZN BOUND BETWEEN 2 MOLECULES

Chain	Residue
C	ASP105
A	GLU94

---

site_id	ZN3
Number of Residues	2
Details

Chain	Residue
B	ASP105
B	HIS84

---

Functional Information from PROSITE/UniProt

site_id	PS00248
Number of Residues	14
Details	NGF_1 Nerve growth factor family signature. GCRGIDskhWnSyC

Chain	Residue	Details
A	GLY67-CYS80

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Binding site: {"description":"in other chain","evidences":[{"source":"PubMed","id":"22649032","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4EAX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Binding site: {"description":"in other chain","evidences":[{"source":"PubMed","id":"26144237","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4XPJ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22649032","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4EAX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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