Functional Information from GO Data
| Chain | GOid | namespace | contents |
| P | 0004175 | molecular_function | endopeptidase activity |
| P | 0004252 | molecular_function | serine-type endopeptidase activity |
| P | 0005576 | cellular_component | extracellular region |
| P | 0005615 | cellular_component | extracellular space |
| P | 0006508 | biological_process | proteolysis |
| P | 0008236 | molecular_function | serine-type peptidase activity |
| P | 0032868 | biological_process | response to insulin |
| P | 0050796 | biological_process | regulation of insulin secretion |
| P | 0090330 | biological_process | regulation of platelet aggregation |
| P | 1901143 | biological_process | insulin catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 1NB P 1 |
| Chain | Residue |
| P | HOH367 |
| P | HIS57 |
| P | SER190 |
| P | CYS191 |
| P | ASN192 |
| P | GLY193 |
| P | ASP194 |
| P | SER195 |
| P | SER214 |
| site_id | CAT |
| Number of Residues | 1 |
| Details | CATALYTIC TRIAD |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| P | LEU53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. SScnGDSGGPLN |
| Chain | Residue | Details |
| P | SER189-ASN200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| P | HIS57 | |
| P | ASP102 | |
| P | SER195 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| P | ASP102 | |
| P | HIS57 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| P | SER195 | |
| P | GLY196 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| P | SER195 | |
| P | GLY193 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| P | ASP102 | |
| P | SER195 | |
| P | HIS57 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| P | ASP102 | |
| P | SER195 | |
| P | HIS57 | |
| P | GLY196 | |
| site_id | CSA6 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| P | ASP102 | |
| P | SER195 | |
| P | GLY193 | |
| P | HIS57 | |
| P | SER214 | |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| P | ASP102 | |
| P | SER195 | |
| P | GLY193 | |
| P | HIS57 | |
