Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004402 | molecular_function | histone acetyltransferase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006325 | biological_process | chromatin organization |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0031509 | biological_process | subtelomeric heterochromatin formation |
| A | 0042393 | molecular_function | histone binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 321 |
| Chain | Residue |
| A | GLU255 |
| A | ASP256 |
| A | ASP256 |
| A | HOH460 |
| site_id | AC2 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE ACO A 400 |
| Chain | Residue |
| A | LYS182 |
| A | SER218 |
| A | GLN219 |
| A | PHE220 |
| A | LEU221 |
| A | ILE222 |
| A | GLN227 |
| A | ASN228 |
| A | LYS229 |
| A | GLY230 |
| A | HIS231 |
| A | GLY232 |
| A | SER233 |
| A | VAL254 |
| A | GLU255 |
| A | ASN258 |
| A | PHE261 |
| A | LEU264 |
| A | ARG267 |
| A | HOH401 |
| A | HOH403 |
| A | HOH417 |
| A | LYS123 |
| A | VAL124 |
| A | SER125 |
| A | GLU126 |
| A | ILE161 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Region: {"description":"Interaction with histone H4 N-terminus","evidences":[{"source":"PubMed","id":"24835250","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"24835250","evidenceCode":"ECO:0000303"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24835250","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9727486","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"9727486","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Site: {"description":"Interaction with histone H4 N-terminus","evidences":[{"source":"PubMed","id":"24835250","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | a catalytic site defined by CSA, PubMed 18373695, 17694075, 10430873, 9727486 |
| Chain | Residue | Details |
| A | GLU255 | |
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 224 |
| Chain | Residue | Details |
| A | PHE220 | electrostatic stabiliser, hydrogen bond donor |
| A | GLU255 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
