1BHF
P56LCK SH2 DOMAIN INHIBITOR COMPLEX
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR CHAIN I OF INHIBITOR ACE-IPA-GLU-GLU-ILE |
| Chain | Residue |
| A | ARG134 |
| A | LYS182 |
| A | TYR209 |
| A | ALA212 |
| A | SER213 |
| A | ASP214 |
| A | GLY215 |
| A | LEU216 |
| A | CYS217 |
| A | THR218 |
| A | ARG219 |
| A | ARG154 |
| A | ARG219 |
| A | SER221 |
| A | HOH301 |
| A | HOH314 |
| A | HOH364 |
| A | HOH374 |
| A | HOH377 |
| I | HOH302 |
| I | HOH308 |
| I | HOH310 |
| A | SER156 |
| I | HOH313 |
| I | HOH315 |
| I | HOH325 |
| I | HOH326 |
| I | HOH327 |
| I | HOH332 |
| I | HOH363 |
| A | GLU157 |
| A | SER158 |
| A | SER164 |
| A | LYS179 |
| A | HIS180 |
| A | TYR181 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 97 |
| Details | Domain: {"description":"SH2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00191","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P06240","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
