1BDG

HEXOKINASE FROM SCHISTOSOMA MANSONI COMPLEXED WITH GLUCOSE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001678	biological_process	intracellular glucose homeostasis
A	0004340	molecular_function	glucokinase activity
A	0004396	molecular_function	hexokinase activity
A	0005524	molecular_function	ATP binding
A	0005536	molecular_function	D-glucose binding
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0005975	biological_process	carbohydrate metabolic process
A	0006006	biological_process	glucose metabolic process
A	0006013	biological_process	mannose metabolic process
A	0006096	biological_process	glycolytic process
A	0008865	molecular_function	fructokinase activity
A	0016301	molecular_function	kinase activity
A	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
A	0019158	molecular_function	mannokinase activity
A	0019318	biological_process	hexose metabolic process
A	0046835	biological_process	carbohydrate phosphorylation
A	0051156	biological_process	glucose 6-phosphate metabolic process

Functional Information from PROSITE/UniProt

site_id	PS00378
Number of Residues	26
Details	HEXOKINASE_1 Hexokinase domain signature. LGFTFSFPcvqkgLThatLvrWTKgF

Chain	Residue	Details
A	LEU150-PHE175

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
A	ASP84

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:9665168

Chain	Residue	Details
A	SER155
A	THR172
A	ASN208
A	THR234
A	GLU260
A	GLU294

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site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P19367

Chain	Residue	Details
A	GLY299
A	THR336
A	SER415

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1ig8

Chain	Residue	Details
A	SER155
A	ASP209
A	ARG170

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