1B8U

MALATE DEHYDROGENASE FROM AQUASPIRILLUM ARCTICUM

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0006099	biological_process	tricarboxylic acid cycle
A	0006107	biological_process	oxaloacetate metabolic process
A	0006108	biological_process	malate metabolic process
A	0006734	biological_process	NADH metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016615	molecular_function	malate dehydrogenase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0019752	biological_process	carboxylic acid metabolic process
A	0030060	molecular_function	L-malate dehydrogenase (NAD+) activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE OAA A 350

Chain	Residue
A	LEU161
A	NAD334
A	HOH356
A	HOH359
A	ARG165
A	HIS190
A	SER191
A	GLY227
A	LYS228
A	ARG229
A	GLY230
A	SER241

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site_id	AC2
Number of Residues	19
Details	BINDING SITE FOR RESIDUE NAD A 334

Chain	Residue
A	THR11
A	GLY12
A	GLY15
A	GLN16
A	ILE17
A	GLU43
A	ILE44
A	VAL90
A	GLY91
A	ALA92
A	GLN115
A	VAL132
A	GLY133
A	ASN134
A	MET158
A	HIS190
A	OAA350
A	HOH367
A	HOH381

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_01517

Chain	Residue	Details
A	HIS190

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01517, ECO:0000269|PubMed:10206992

Chain	Residue	Details
A	GLY12
A	GLN115
A	VAL132

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site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01517

Chain	Residue	Details
A	ARG95
A	ARG101
A	ASN108
A	ASN134

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site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01517, ECO:0000305|PubMed:10206992

Chain	Residue	Details
A	ARG165

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1emd

Chain	Residue	Details
A	ASN189
A	ASP162

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site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1emd

Chain	Residue	Details
A	ARG165
A	HIS190
A	ASP162

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