1B74
GLUTAMATE RACEMASE FROM AQUIFEX PYROPHILUS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006807 | biological_process | nitrogen compound metabolic process |
| A | 0008360 | biological_process | regulation of cell shape |
| A | 0008881 | molecular_function | glutamate racemase activity |
| A | 0009252 | biological_process | peptidoglycan biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016855 | molecular_function | racemase and epimerase activity, acting on amino acids and derivatives |
| A | 0036361 | molecular_function | racemase activity, acting on amino acids and derivatives |
| A | 0071555 | biological_process | cell wall organization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE DGN A 538 |
| Chain | Residue |
| A | ALA69 |
| A | CYS70 |
| A | ASN71 |
| A | GLU147 |
| A | GLY177 |
| A | CYS178 |
| A | HOH540 |
| A | HOH599 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000250|UniProtKB:O58403, ECO:0000255|HAMAP-Rule:MF_00258 |
| Chain | Residue | Details |
| A | CYS70 | |
| A | CYS178 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P22634, ECO:0000255|HAMAP-Rule:MF_00258 |
| Chain | Residue | Details |
| A | TYR39 | |
| A | THR179 | |
| A | ASP7 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00258, ECO:0000269|PubMed:10331867, ECO:0007744|PDB:1B74 |
| Chain | Residue | Details |
| A | ASN71 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:10331867, ECO:0007744|PDB:1B74 |
| Chain | Residue | Details |
| A | GLU147 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 1 |
| Chain | Residue | Details |
| A | ASP7 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor |
| A | SER8 | electrostatic stabiliser, hydrogen bond donor, increase basicity |
| A | CYS70 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | GLU147 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, increase basicity, proton donor |
| A | CYS178 | activator, hydrogen bond acceptor, proton acceptor, proton donor |
| A | HIS180 | electrostatic stabiliser, hydrogen bond donor |
