1B72
PBX1, HOMEOBOX PROTEIN HOX-B1/DNA TERNARY COMPLEX
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0006357 | biological_process | regulation of transcription by RNA polymerase II |
| A | 0043565 | molecular_function | sequence-specific DNA binding |
| B | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| B | 0003677 | molecular_function | DNA binding |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PROSITE/UniProt
| site_id | PS00027 |
| Number of Residues | 24 |
| Details | HOMEOBOX_1 'Homeobox' domain signature. LAkkCgITvsQVSNWFgNkriryK |
| Chain | Residue | Details |
| B | LEU269-LYS292 | |
| A | ILE236-LYS259 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 62 |
| Details | DNA_BIND: Homeobox; TALE-type => ECO:0000255|PROSITE-ProRule:PRU00108 |
| Chain | Residue | Details |
| B | ALA233-ILE295 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Required for binding to the NFIL3 promoter => ECO:0000250|UniProtKB:P41778 |
| Chain | Residue | Details |
| B | ASN286 |
