1B56

HUMAN RECOMBINANT EPIDERMAL FATTY ACID BINDING PROTEIN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001972	molecular_function	retinoic acid binding
A	0005319	molecular_function	lipid transporter activity
A	0005324	molecular_function	long-chain fatty acid transmembrane transporter activity
A	0005504	molecular_function	fatty acid binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006629	biological_process	lipid metabolic process
A	0006869	biological_process	lipid transport
A	0008289	molecular_function	lipid binding
A	0008544	biological_process	epidermis development
A	0014069	cellular_component	postsynaptic density
A	0015908	biological_process	fatty acid transport
A	0015909	biological_process	long-chain fatty acid transport
A	0019433	biological_process	triglyceride catabolic process
A	0030667	cellular_component	secretory granule membrane
A	0031392	biological_process	regulation of prostaglandin biosynthetic process
A	0035360	biological_process	positive regulation of peroxisome proliferator activated receptor signaling pathway
A	0035578	cellular_component	azurophil granule lumen
A	0042802	molecular_function	identical protein binding
A	0045202	cellular_component	synapse
A	0051930	biological_process	regulation of sensory perception of pain
A	0070062	cellular_component	extracellular exosome
A	0098921	biological_process	retrograde trans-synaptic signaling by endocannabinoid
A	0098978	cellular_component	glutamatergic synapse
A	0099092	cellular_component	postsynaptic density, intracellular component
A	0099178	biological_process	regulation of retrograde trans-synaptic signaling by endocanabinoid
A	0099524	cellular_component	postsynaptic cytosol
A	0120162	biological_process	positive regulation of cold-induced thermogenesis
A	1990379	biological_process	lipid transport across blood-brain barrier

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PLM A 136

Chain	Residue
A	MET35
A	HOH236
A	GLY36
A	ASP79
A	ARG109
A	VAL118
A	ARG129
A	TYR131
A	HOH213
A	HOH214

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Functional Information from PROSITE/UniProt

site_id	PS00214
Number of Residues	18
Details	FABP Cytosolic fatty-acid binding proteins signature. GRWrLvdSkGFDeYMKEL

Chain	Residue	Details
A	GLY9-LEU26

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Motif: {"description":"Nuclear localization signal","evidences":[{"source":"PubMed","id":"24692551","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"24531463","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4AZR","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"24692551","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4LKT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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