Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004156 | molecular_function | dihydropteroate synthase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
A | 0009410 | biological_process | response to xenobiotic stimulus |
A | 0016740 | molecular_function | transferase activity |
A | 0042558 | biological_process | pteridine-containing compound metabolic process |
A | 0044237 | biological_process | cellular metabolic process |
A | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
A | 0046656 | biological_process | folic acid biosynthetic process |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 A 284 |
Chain | Residue |
A | ASN22 |
A | ARG63 |
A | ARG255 |
A | HIS257 |
A | HOH312 |
A | PH2559 |
A | SAN561 |
site_id | AC2 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE PH2 A 559 |
Chain | Residue |
A | ASN115 |
A | ILE117 |
A | ASP185 |
A | PHE190 |
A | LEU215 |
A | GLY217 |
A | LYS221 |
A | ARG255 |
A | SO4284 |
A | HOH419 |
A | SAN561 |
A | THR62 |
A | ASP96 |
site_id | AC3 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SAN A 561 |
Chain | Residue |
A | THR62 |
A | ARG63 |
A | SER219 |
A | ARG220 |
A | LYS221 |
A | HIS257 |
A | SO4284 |
A | PH2559 |
Functional Information from PROSITE/UniProt
site_id | PS00792 |
Number of Residues | 16 |
Details | DHPS_1 Dihydropteroate synthase signature 1. VmGILNvTpDSFsDgG |
Chain | Residue | Details |
A | VAL17-GLY32 | |
site_id | PS00793 |
Number of Residues | 14 |
Details | DHPS_2 Dihydropteroate synthase signature 2. GAtIIDVGGesTrP |
Chain | Residue | Details |
A | GLY51-PRO64 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASN22 | |
Chain | Residue | Details |
A | THR62 | |
A | ASP96 | |
A | ASN115 | |
A | ASP185 | |
A | LYS221 | |
A | ARG255 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | a catalytic site defined by CSA, PubMed 11007651, 9149138, 9187658 |
Chain | Residue | Details |
A | LYS221 | |
A | ARG255 | |
site_id | MCSA1 |
Number of Residues | 2 |
Details | M-CSA 394 |
Chain | Residue | Details |
A | LYS221 | activator |
A | ARG255 | activator |