1A7G

THE CRYSTAL STRUCTURE OF THE E2 DNA-BINDING DOMAIN FROM HUMAN PAPILLOMAVIRUS AT 2.4 ANGSTROMS

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0003677	molecular_function	DNA binding
E	0003700	molecular_function	DNA-binding transcription factor activity
E	0006275	biological_process	regulation of DNA replication
E	0006355	biological_process	regulation of DNA-templated transcription
E	0042025	cellular_component	host cell nucleus

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 E 1

Chain	Residue
E	HOH49
E	LYS306
E	ARG309
E	SER324
E	THR325

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 E 2

Chain	Residue
E	TRP326
E	TRP326
E	THR341
E	THR341
E	ILE295
E	ILE295
E	HIS297
E	HIS297

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	80
Details	Region: {"description":"DNA-binding domain","evidences":[{"source":"HAMAP-Rule","id":"MF_04001","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)","evidences":[{"source":"HAMAP-Rule","id":"MF_04001","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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