1A76

FLAP ENDONUCLEASE-1 FROM METHANOCOCCUS JANNASCHII

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003677	molecular_function	DNA binding
A	0003824	molecular_function	catalytic activity
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004527	molecular_function	exonuclease activity
A	0006260	biological_process	DNA replication
A	0006281	biological_process	DNA repair
A	0008409	molecular_function	5'-3' exonuclease activity
A	0016788	molecular_function	hydrolase activity, acting on ester bonds
A	0017108	molecular_function	5'-flap endonuclease activity
A	0043137	biological_process	DNA replication, removal of RNA primer
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN A 340

Chain	Residue
A	GLU154
A	HOH343
A	HOH459
A	HOH516
A	HOH517

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MN A 341

Chain	Residue
A	ASP175
A	ASP224
A	HOH394

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00614

Chain	Residue	Details
A	ASP27
A	ASP80
A	ASP173
A	ASP175

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:9699635, ECO:0007744|PDB:1A77

Chain	Residue	Details
A	GLU152

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:9699635, ECO:0007744|PDB:1A76, ECO:0007744|PDB:1A77

Chain	Residue	Details
A	GLU154
A	ASP224

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1exn

Chain	Residue	Details
A	ARG95

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