Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003779 | molecular_function | actin binding |
A | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006096 | biological_process | glycolytic process |
A | 0016020 | cellular_component | membrane |
A | 0016829 | molecular_function | lyase activity |
A | 0020002 | cellular_component | host cell plasma membrane |
A | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
B | 0003779 | molecular_function | actin binding |
B | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0006096 | biological_process | glycolytic process |
B | 0016020 | cellular_component | membrane |
B | 0016829 | molecular_function | lyase activity |
B | 0020002 | cellular_component | host cell plasma membrane |
B | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
Functional Information from PROSITE/UniProt
site_id | PS00158 |
Number of Residues | 11 |
Details | ALDOLASE_CLASS_I Fructose-bisphosphate aldolase class-I active site. VlLEGaLLKPN |
Chain | Residue | Details |
A | VAL228-ASN238 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | GLU194 | |
B | GLU194 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: Schiff-base intermediate with dihydroxyacetone phosphate => ECO:0000250|UniProtKB:Q8I8I2 |
Chain | Residue | Details |
A | LYS236 | |
B | LYS236 | |
Chain | Residue | Details |
A | ASP39 | |
A | GLY308 | |
A | ARG309 | |
B | ASP39 | |
B | SER41 | |
B | THR44 | |
B | LYS112 | |
B | LYS151 | |
B | GLU194 | |
B | LYS236 | |
B | SER278 | |
A | SER41 | |
B | GLY279 | |
B | GLY308 | |
B | ARG309 | |
A | THR44 | |
A | LYS112 | |
A | LYS151 | |
A | GLU194 | |
A | LYS236 | |
A | SER278 | |
A | GLY279 | |
Chain | Residue | Details |
A | ARG48 | |
A | SER306 | |
B | ARG48 | |
B | SER306 | |
site_id | SWS_FT_FI5 |
Number of Residues | 2 |
Details | SITE: Necessary for preference for fructose 1,6-bisphosphate over fructose 1-phosphate => ECO:0000250|UniProtKB:P00883 |
Chain | Residue | Details |
A | TYR368 | |
B | TYR368 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ald |
Chain | Residue | Details |
A | LYS236 | |
A | ASP39 | |
A | GLU194 | |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ald |
Chain | Residue | Details |
B | LYS236 | |
B | ASP39 | |
B | GLU194 | |