1A4E
CATALASE A FROM SACCHAROMYCES CEREVISIAE
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000302 | biological_process | response to reactive oxygen species |
A | 0004096 | molecular_function | catalase activity |
A | 0004601 | molecular_function | peroxidase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005739 | cellular_component | mitochondrion |
A | 0005759 | cellular_component | mitochondrial matrix |
A | 0005777 | cellular_component | peroxisome |
A | 0005782 | cellular_component | peroxisomal matrix |
A | 0006979 | biological_process | response to oxidative stress |
A | 0020037 | molecular_function | heme binding |
A | 0042542 | biological_process | response to hydrogen peroxide |
A | 0042744 | biological_process | hydrogen peroxide catabolic process |
A | 0046872 | molecular_function | metal ion binding |
A | 0098869 | biological_process | cellular oxidant detoxification |
B | 0000302 | biological_process | response to reactive oxygen species |
B | 0004096 | molecular_function | catalase activity |
B | 0004601 | molecular_function | peroxidase activity |
B | 0005515 | molecular_function | protein binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0005739 | cellular_component | mitochondrion |
B | 0005759 | cellular_component | mitochondrial matrix |
B | 0005777 | cellular_component | peroxisome |
B | 0005782 | cellular_component | peroxisomal matrix |
B | 0006979 | biological_process | response to oxidative stress |
B | 0020037 | molecular_function | heme binding |
B | 0042542 | biological_process | response to hydrogen peroxide |
B | 0042744 | biological_process | hydrogen peroxide catabolic process |
B | 0046872 | molecular_function | metal ion binding |
B | 0098869 | biological_process | cellular oxidant detoxification |
C | 0000302 | biological_process | response to reactive oxygen species |
C | 0004096 | molecular_function | catalase activity |
C | 0004601 | molecular_function | peroxidase activity |
C | 0005515 | molecular_function | protein binding |
C | 0005737 | cellular_component | cytoplasm |
C | 0005739 | cellular_component | mitochondrion |
C | 0005759 | cellular_component | mitochondrial matrix |
C | 0005777 | cellular_component | peroxisome |
C | 0005782 | cellular_component | peroxisomal matrix |
C | 0006979 | biological_process | response to oxidative stress |
C | 0020037 | molecular_function | heme binding |
C | 0042542 | biological_process | response to hydrogen peroxide |
C | 0042744 | biological_process | hydrogen peroxide catabolic process |
C | 0046872 | molecular_function | metal ion binding |
C | 0098869 | biological_process | cellular oxidant detoxification |
D | 0000302 | biological_process | response to reactive oxygen species |
D | 0004096 | molecular_function | catalase activity |
D | 0004601 | molecular_function | peroxidase activity |
D | 0005515 | molecular_function | protein binding |
D | 0005737 | cellular_component | cytoplasm |
D | 0005739 | cellular_component | mitochondrion |
D | 0005759 | cellular_component | mitochondrial matrix |
D | 0005777 | cellular_component | peroxisome |
D | 0005782 | cellular_component | peroxisomal matrix |
D | 0006979 | biological_process | response to oxidative stress |
D | 0020037 | molecular_function | heme binding |
D | 0042542 | biological_process | response to hydrogen peroxide |
D | 0042744 | biological_process | hydrogen peroxide catabolic process |
D | 0046872 | molecular_function | metal ion binding |
D | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE AZI A 504 |
Chain | Residue |
A | HIS70 |
A | ASN143 |
A | PHE148 |
A | PHE156 |
A | HEM503 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE AZI B 504 |
Chain | Residue |
B | PHE156 |
B | HEM503 |
B | PRO69 |
B | HIS70 |
B | ASN143 |
B | PHE148 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE AZI C 504 |
Chain | Residue |
C | PRO69 |
C | HIS70 |
C | ASN143 |
C | PHE148 |
C | PHE156 |
C | HEM503 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE AZI D 504 |
Chain | Residue |
D | PRO69 |
D | HIS70 |
D | ASN143 |
D | PHE148 |
D | PHE156 |
D | HEM503 |
site_id | AC5 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 A 1 |
Chain | Residue |
A | ARG61 |
B | ARG360 |
B | TYR361 |
B | HOH608 |
C | ARG61 |
D | ARG360 |
D | TYR361 |
D | HOH601 |
site_id | AC6 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 D 2 |
Chain | Residue |
A | ARG360 |
A | TYR361 |
A | HOH604 |
B | ARG61 |
C | ARG360 |
C | TYR361 |
C | HOH606 |
D | ARG61 |
site_id | AC7 |
Number of Residues | 24 |
Details | BINDING SITE FOR RESIDUE HEM A 503 |
Chain | Residue |
A | ARG67 |
A | ASN68 |
A | PRO69 |
A | HIS70 |
A | ARG107 |
A | GLY126 |
A | VAL141 |
A | TYR142 |
A | ASN143 |
A | PHE156 |
A | SER213 |
A | PHE331 |
A | VAL347 |
A | ARG351 |
A | SER354 |
A | TYR355 |
A | ALA358 |
A | HIS359 |
A | ARG362 |
A | AZI504 |
A | HOH506 |
A | HOH509 |
A | HOH514 |
D | ASN60 |
site_id | AC8 |
Number of Residues | 23 |
Details | BINDING SITE FOR RESIDUE HEM B 503 |
Chain | Residue |
B | ARG67 |
B | ASN68 |
B | HIS70 |
B | ARG107 |
B | GLY126 |
B | VAL141 |
B | TYR142 |
B | ASN143 |
B | PHE156 |
B | SER213 |
B | HIS215 |
B | PHE331 |
B | VAL347 |
B | ARG351 |
B | SER354 |
B | TYR355 |
B | HIS359 |
B | ARG362 |
B | AZI504 |
B | HOH511 |
B | HOH515 |
B | HOH523 |
C | ASN60 |
site_id | AC9 |
Number of Residues | 24 |
Details | BINDING SITE FOR RESIDUE HEM C 503 |
Chain | Residue |
C | VAL347 |
C | ARG351 |
C | SER354 |
C | TYR355 |
C | ALA358 |
C | HIS359 |
C | ARG362 |
C | AZI504 |
C | HOH510 |
C | HOH515 |
C | HOH521 |
B | ASN60 |
C | ARG67 |
C | ASN68 |
C | HIS70 |
C | ARG107 |
C | GLY126 |
C | VAL141 |
C | TYR142 |
C | ASN143 |
C | PHE148 |
C | PHE156 |
C | SER213 |
C | PHE331 |
site_id | BC1 |
Number of Residues | 24 |
Details | BINDING SITE FOR RESIDUE HEM D 503 |
Chain | Residue |
A | ASN60 |
D | ARG67 |
D | ASN68 |
D | HIS70 |
D | ARG107 |
D | GLY126 |
D | VAL141 |
D | TYR142 |
D | ASN143 |
D | PHE148 |
D | PHE156 |
D | SER213 |
D | PHE331 |
D | VAL347 |
D | ARG351 |
D | SER354 |
D | TYR355 |
D | ALA358 |
D | HIS359 |
D | ARG362 |
D | AZI504 |
D | HOH517 |
D | HOH521 |
D | HOH526 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 8 |
Details | ACT_SITE: ACT_SITE => ECO:0000269|PubMed:9931255 |
Chain | Residue | Details |
A | HIS70 | |
A | ASN143 | |
B | HIS70 | |
B | ASN143 | |
C | HIS70 | |
C | ASN143 | |
D | HIS70 | |
D | ASN143 |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | BINDING: axial binding residue => ECO:0000269|PubMed:9931255 |
Chain | Residue | Details |
A | TYR355 | |
B | TYR355 | |
C | TYR355 | |
D | TYR355 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1iph |
Chain | Residue | Details |
A | SER109 | |
A | ASN143 | |
A | HIS70 |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1iph |
Chain | Residue | Details |
B | SER109 | |
B | ASN143 | |
B | HIS70 |
site_id | CSA3 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1iph |
Chain | Residue | Details |
C | SER109 | |
C | ASN143 | |
C | HIS70 |
site_id | CSA4 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1iph |
Chain | Residue | Details |
D | SER109 | |
D | ASN143 | |
D | HIS70 |