1A3A

CRYSTAL STRUCTURE OF IIA MANNITOL FROM ESCHERICHIA COLI

Functional Information from PROSITE/UniProt

site_id	PS00372
Number of Residues	17
Details	PTS_EIIA_TYPE_2_HIS PTS EIIA domains phosphorylation site signature 2. EkltptyLGesIAVPHG

Chain	Residue	Details
A	GLU50-GLY66

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	426
Details	Domain: {"description":"PTS EIIA type-2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00417","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Active site: {"description":"Tele-phosphohistidine intermediate; for EIIA activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00417","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12202490","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"16443929","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9551558","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Site: {"description":"Stabilizes the transition state in the phosphoryl transfer from HPr to EIIA","evidences":[{"source":"PubMed","id":"9551558","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	4
Details	Modified residue: {"description":"Phosphohistidine; by HPr","evidences":[{"source":"PubMed","id":"3142516","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12202490","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"16443929","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"2407724","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9551558","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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