1A3A
CRYSTAL STRUCTURE OF IIA MANNITOL FROM ESCHERICHIA COLI
Functional Information from PROSITE/UniProt
| site_id | PS00372 |
| Number of Residues | 17 |
| Details | PTS_EIIA_TYPE_2_HIS PTS EIIA domains phosphorylation site signature 2. EkltptyLGesIAVPHG |
| Chain | Residue | Details |
| A | GLU50-GLY66 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Tele-phosphohistidine intermediate; for EIIA activity => ECO:0000255|PROSITE-ProRule:PRU00417, ECO:0000305|PubMed:12202490, ECO:0000305|PubMed:16443929, ECO:0000305|PubMed:9551558 |
| Chain | Residue | Details |
| A | HIS65 | |
| B | HIS65 | |
| C | HIS65 | |
| D | HIS65 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Stabilizes the transition state in the phosphoryl transfer from HPr to EIIA => ECO:0000269|PubMed:9551558 |
| Chain | Residue | Details |
| A | ARG49 | |
| B | ARG49 | |
| C | ARG49 | |
| D | ARG49 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphohistidine; by HPr => ECO:0000269|PubMed:3142516, ECO:0000305|PubMed:12202490, ECO:0000305|PubMed:16443929, ECO:0000305|PubMed:2407724, ECO:0000305|PubMed:9551558 |
| Chain | Residue | Details |
| A | HIS65 | |
| B | HIS65 | |
| C | HIS65 | |
| D | HIS65 |
