1A1J

RADR (ZIF268 VARIANT) ZINC FINGER-DNA COMPLEX (GCGT SITE)

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 201

Chain	Residue
A	CYS107
A	CYS112
A	HIS125
A	HIS129

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 202

Chain	Residue
A	CYS137
A	CYS140
A	HIS153
A	HIS157

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 203

Chain	Residue
A	CYS168
A	HIS181
A	HIS185
A	CYS165

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Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	23
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. CpvesCdrrFsrsadltrHiri..H

Chain	Residue	Details
A	CYS107-HIS129
A	CYS137-HIS157
A	CYS165-HIS185

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	ZN_FING: C2H2-type 1 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	THR130-ILE154

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site_id	SWS_FT_FI2
Number of Residues	22
Details	ZN_FING: C2H2-type 2 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	GLU160-THR182

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site_id	SWS_FT_FI3
Number of Residues	6
Details	SITE: Interaction with DNA => ECO:0000269|PubMed:2028256, ECO:0000269|PubMed:8939742, ECO:0007744|PDB:1AAY, ECO:0007744|PDB:1ZAA

Chain	Residue	Details
A	ILE128
A	ILE139
A	ASN143
A	HIS149
A	ILE167
A	LYS171

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