10OZ
Structure of PDE5 PDE6 chimera
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0001750 | cellular_component | photoreceptor outer segment |
| C | 0004857 | molecular_function | enzyme inhibitor activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0007601 | biological_process | visual perception |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0042622 | cellular_component | photoreceptor outer segment membrane |
| C | 0045742 | biological_process | positive regulation of epidermal growth factor receptor signaling pathway |
| C | 0045745 | biological_process | positive regulation of G protein-coupled receptor signaling pathway |
| C | 0060090 | molecular_function | molecular adaptor activity |
| C | 0097381 | cellular_component | photoreceptor disc membrane |
| D | 0001750 | cellular_component | photoreceptor outer segment |
| D | 0004857 | molecular_function | enzyme inhibitor activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0007601 | biological_process | visual perception |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0042622 | cellular_component | photoreceptor outer segment membrane |
| D | 0045742 | biological_process | positive regulation of epidermal growth factor receptor signaling pathway |
| D | 0045745 | biological_process | positive regulation of G protein-coupled receptor signaling pathway |
| D | 0060090 | molecular_function | molecular adaptor activity |
| D | 0097381 | cellular_component | photoreceptor disc membrane |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHrGvnNsY |
| Chain | Residue | Details |
| A | HIS578-TYR589 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 338 |
| Details | Domain: {"description":"GAF 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01434","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"O76083","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"O76074","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 324 |
| Details | Domain: {"description":"PDEase","evidences":[{"source":"PROSITE-ProRule","id":"PRU01192","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
