10ID

Membrane-bound, reversed VP5* trimer (rotavirus spike protein)

Functional Information from GO Data

Chain	GOid	namespace	contents
2	0019028	cellular_component	viral capsid
2	0019062	biological_process	virion attachment to host cell
2	0020002	cellular_component	host cell plasma membrane
2	0039624	cellular_component	viral outer capsid
2	0039665	biological_process	permeabilization of host organelle membrane involved in viral entry into host cell
2	0044163	cellular_component	host cytoskeleton
2	0044168	cellular_component	host cell rough endoplasmic reticulum
2	0044172	cellular_component	host cell endoplasmic reticulum-Golgi intermediate compartment
2	0046718	biological_process	symbiont entry into host cell
2	0140267	biological_process	symbiont entry into host cell via permeabilization of host membrane
3	0019028	cellular_component	viral capsid
3	0019062	biological_process	virion attachment to host cell
3	0020002	cellular_component	host cell plasma membrane
3	0039624	cellular_component	viral outer capsid
3	0039665	biological_process	permeabilization of host organelle membrane involved in viral entry into host cell
3	0044163	cellular_component	host cytoskeleton
3	0044168	cellular_component	host cell rough endoplasmic reticulum
3	0044172	cellular_component	host cell endoplasmic reticulum-Golgi intermediate compartment
3	0046718	biological_process	symbiont entry into host cell
3	0140267	biological_process	symbiont entry into host cell via permeabilization of host membrane
4	0019028	cellular_component	viral capsid
4	0019062	biological_process	virion attachment to host cell
4	0020002	cellular_component	host cell plasma membrane
4	0039624	cellular_component	viral outer capsid
4	0039665	biological_process	permeabilization of host organelle membrane involved in viral entry into host cell
4	0044163	cellular_component	host cytoskeleton
4	0044168	cellular_component	host cell rough endoplasmic reticulum
4	0044172	cellular_component	host cell endoplasmic reticulum-Golgi intermediate compartment
4	0046718	biological_process	symbiont entry into host cell
4	0140267	biological_process	symbiont entry into host cell via permeabilization of host membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	693
Details	Region: {"description":"Spike body and stalk (antigen domain)","evidences":[{"source":"HAMAP-Rule","id":"MF_04132","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21157433","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	60
Details	Region: {"description":"Hydrophobic; possible role in virus entry into host cell","evidences":[{"source":"HAMAP-Rule","id":"MF_04132","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"20375171","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	81
Details	Coiled coil: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04132","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21157433","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Motif: {"description":"DGE motif; interaction with ITGA2/ITGB1 heterodimer","evidences":[{"source":"HAMAP-Rule","id":"MF_04132","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11112480","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	Motif: {"description":"YGL motif; interaction with ITGA4","evidences":[{"source":"HAMAP-Rule","id":"MF_04132","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16298987","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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