9HYN
CRYSTAL STRUCTURE OF THE SMARCA2-VCB-COMPLEX WITH PROTAC P1
This is a non-PDB format compatible entry.
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X10SA |
| Synchrotron site | SLS |
| Beamline | X10SA |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2018-12-05 |
| Detector | DECTRIS PILATUS 6M-F |
| Wavelength(s) | 0.99991 |
| Spacegroup name | P 21 21 21 |
| Unit cell lengths | 79.941, 118.226, 122.702 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 45.010 - 2.370 |
| R-factor | 0.247 |
| Rwork | 0.246 |
| R-free | 0.26200 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.008 |
| RMSD bond angle | 0.970 |
| Data reduction software | XDS |
| Data scaling software | STARANISO |
| Phasing software | BUSTER |
| Refinement software | BUSTER (2.11.7) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 85.140 | 2.491 |
| High resolution limit [Å] | 2.366 | 2.366 |
| Number of reflections | 40863 | 1523 |
| <I/σ(I)> | 16.6 | |
| Completeness [%] | 94.4 | |
| Redundancy | 10.3 | |
| CC(1/2) | 0.998 | 0.608 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, SITTING DROP | 293 | 0.1 M K2HPO4 16 % PEG 8000 0.2 M sodium chloride |
