9FZA
TEAD1/YAP in complex with a reversible inhibitor N-[(4-phenoxyphenyl)methyl]imidazo[1,2-a]pyridine-3-carboxamide
This is a non-PDB format compatible entry.
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X06SA |
| Synchrotron site | SLS |
| Beamline | X06SA |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2018-03-02 |
| Detector | DECTRIS PILATUS 6M |
| Wavelength(s) | 0.99998 |
| Spacegroup name | P 21 21 21 |
| Unit cell lengths | 43.992, 106.498, 166.162 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 50.710 - 2.214 |
| R-factor | 0.2237 |
| Rwork | 0.222 |
| R-free | 0.26220 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.008 |
| RMSD bond angle | 0.920 |
| Data reduction software | XDS |
| Data scaling software | XDS |
| Phasing software | PHASER |
| Refinement software | BUSTER (2.11.8 (23-JAN-2024)) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 50.710 | 2.551 |
| High resolution limit [Å] | 2.214 | 2.214 |
| Rmeas | 0.066 | |
| Rpim | 0.024 | 0.338 |
| Number of reflections | 19089 | 954 |
| <I/σ(I)> | 16.7 | |
| Completeness [%] | 90.2 | |
| Redundancy | 6.2 | |
| CC(1/2) | 1.000 | 0.789 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, SITTING DROP | 4.6 | 293 | 2M Sodium Formate, 0.1M Sodium Acetate pH 4.6 |
