9FL3

Crystal structure of IL-17A in complex with compound 26

This is a non-PDB format compatible entry.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SLS BEAMLINE X10SA
Synchrotron site	SLS
Beamline	X10SA
Temperature [K]	100
Detector technology	PIXEL
Collection date	2022-02-27
Detector	DECTRIS EIGER X 16M
Wavelength(s)	0.99988
Spacegroup name	C 2 2 21
Unit cell lengths	64.456, 84.581, 119.286
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	59.640 - 2.068
R-factor	0.2299
Rwork	0.229
R-free	0.25240
Structure solution method	FOURIER SYNTHESIS
RMSD bond length	0.008
RMSD bond angle	0.990
Data reduction software	autoPROC
Data scaling software	Aimless
Phasing software	BUSTER
Refinement software	BUSTER (2.11.8)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	59.643	2.104
High resolution limit [Å]	2.068	2.068
Rmerge	0.068	3.593
Rmeas	0.072	3.769
Rpim	0.023	1.193
Number of reflections	20290	991
<I/σ(I)>	13.5	0.7
Completeness [%]	100.0	100
Redundancy	10	10
CC(1/2)	0.999	0.365

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION		293	0.1M citrate pH 5.5 10% PEG 10,000 12% isopropanol 10% ethylene glycol