9T07
HUMAN PI3KDELTA IN COMPLEX WITH Roginolisib
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X06SA |
| Synchrotron site | SLS |
| Beamline | X06SA |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2011-02-07 |
| Detector | DECTRIS PILATUS 6M |
| Wavelength(s) | 0.9999 |
| Spacegroup name | P 21 21 21 |
| Unit cell lengths | 93.032, 113.387, 144.506 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 46.520 - 2.750 |
| R-factor | 0.2318 |
| Rwork | 0.231 |
| R-free | 0.27250 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Starting model (for MR) | NONE |
| RMSD bond length | 0.007 |
| RMSD bond angle | 0.850 |
| Data reduction software | XDS |
| Data scaling software | XSCALE |
| Phasing software | PHASER |
| Refinement software | BUSTER (2.11.8 (17-JUL-2025)) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 89.200 | 3.000 |
| High resolution limit [Å] | 2.750 | 2.750 |
| Rmeas | 0.040 | 0.493 |
| Number of reflections | 39134 | 8981 |
| <I/σ(I)> | 24.06 | 3.23 |
| Completeness [%] | 96.7 | 97.9 |
| Redundancy | 4.8 | 4.9 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION | 293 | 16% PEG6000, 0.10 M KCL, 0.10 M MES pH 6.0 |
