9GVN

DEPEMOKIMAB FAB IN COMPLEX WITH INTERLEUKIN 5

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	DIAMOND BEAMLINE I02
Synchrotron site	Diamond
Beamline	I02
Temperature [K]	100
Detector technology	PIXEL
Collection date	2016-06-20
Detector	DECTRIS PILATUS 6M
Wavelength(s)	0.97949
Spacegroup name	P 1 21 1
Unit cell lengths	86.684, 65.870, 193.754
Unit cell angles	90.00, 96.62, 90.00

Refinement procedure

Resolution	192.460 - 1.933
R-factor	0.1846
Rwork	0.183
R-free	0.20870
Structure solution method	FOURIER SYNTHESIS
RMSD bond length	0.008
RMSD bond angle	0.990
Data reduction software	autoPROC (1.1.7)
Data scaling software	autoPROC (1.1.7)
Refinement software	BUSTER (2.11.8 (16-JUL-2021))

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	192.462	2.199
High resolution limit [Å]	1.933	1.933
Rmerge	0.043	0.560
Rmeas	0.051	0.663
Rpim	0.028	0.351
Number of reflections	90317	4516
<I/σ(I)>	13.7	2
Completeness [%]	55.5
Redundancy	3.4
CC(1/2)	0.999	0.724

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		293	Morpheus EDO_P8K, Morpheus Carboxylic acids, Morpheus buffer system 2