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8SS9

Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK and antiepileptic drug perampanel (closed state)

EM specimen
VitrificationYes
InstrumentFEI VITROBOT MARK IV
EM Data Collection
MicroscopeFEI TITAN KRIOS
Electron GunFIELD EMISSION GUN
Accelerating Voltage (kV)300
Cs (mm)2.7
DetectorFEI FALCON IV (4k x 4k)
3D Reconstruction
MethodSINGLE PARTICLE
Resolution (Å)2.72
SoftwarePHENIX
SymmetryC2
CTF correctionPHASE FLIPPING AND AMPLITUDE CORRECTION

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PDB entries from 2024-11-06

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