8GJS
Stapled Peptide ALRN-6924 Bound to MDMX
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X10SA |
| Synchrotron site | SLS |
| Beamline | X10SA |
| Temperature [K] | 80 |
| Detector technology | PIXEL |
| Collection date | 2012-04-30 |
| Detector | DECTRIS PILATUS 6M |
| Wavelength(s) | 0.99997 |
| Spacegroup name | C 2 2 21 |
| Unit cell lengths | 81.513, 108.942, 31.434 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 33.170 - 1.750 |
| R-factor | 0.203 |
| Rwork | 0.202 |
| R-free | 0.21700 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.004 |
| RMSD bond angle | 0.700 |
| Data reduction software | HKL-2000 |
| Data scaling software | SCALA |
| Phasing software | CNX |
| Refinement software | CNX |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 33.170 | 1.640 |
| High resolution limit [Å] | 1.560 | 1.560 |
| Rmeas | 0.061 | 1.148 |
| Rpim | 0.024 | 0.458 |
| Total number of observations | 128319 | 18142 |
| Number of reflections | 20439 | 2917 |
| <I/σ(I)> | 14.4 | 1.7 |
| Completeness [%] | 99.9 | |
| Redundancy | 6.3 | 6.2 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION | 277 | PEG 4000,sodium chloride |
