8V4X
Structure of MALT1 in complex with an allosteric inhibitor
This is a non-PDB format compatible entry.
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | APS BEAMLINE 17-ID |
| Synchrotron site | APS |
| Beamline | 17-ID |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2019-02-21 |
| Detector | DECTRIS PILATUS 6M |
| Wavelength(s) | 1.000 |
| Spacegroup name | P 1 21 1 |
| Unit cell lengths | 135.320, 78.770, 135.880 |
| Unit cell angles | 90.00, 112.52, 90.00 |
Refinement procedure
| Resolution | 34.900 - 2.486 |
| R-factor | 0.2129 |
| Rwork | 0.209 |
| R-free | 0.28520 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.007 |
| RMSD bond angle | 0.930 |
| Data reduction software | autoPROC |
| Data scaling software | XDS |
| Phasing software | MOLREP |
| Refinement software | BUSTER (2.11.8) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 125.521 | 2.817 |
| High resolution limit [Å] | 2.486 | 2.486 |
| Number of reflections | 51037 | 2554 |
| <I/σ(I)> | 7.2 | |
| Completeness [%] | 91.9 | 67.5 |
| Redundancy | 3.4 | |
| CC(1/2) | 0.996 | 0.564 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, SITTING DROP | 5.5 | 290 | 16% (w/v) PEG 8000, 0.1 M sodium citrate pH 5.5 |
