7OW6
Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS G12D peptide (VVVGADGVGK)
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | DIAMOND BEAMLINE I04 |
Synchrotron site | Diamond |
Beamline | I04 |
Temperature [K] | 100 |
Detector technology | PIXEL |
Collection date | 2020-12-03 |
Detector | DECTRIS EIGER2 XE 16M |
Wavelength(s) | 0.9795 |
Spacegroup name | P 41 2 2 |
Unit cell lengths | 144.156, 144.156, 119.592 |
Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
Data quality characteristics
Overall | Outer shell | |
Low resolution limit [Å] | 64.470 | 2.690 |
High resolution limit [Å] | 2.640 | 2.640 |
Rmerge | 0.115 | 4.760 |
Rmeas | 0.118 | 4.848 |
Rpim | 0.023 | 0.916 |
Number of reflections | 37600 | 1851 |
<I/σ(I)> | 18.1 | 0.4 |
Completeness [%] | 100.0 | 99.89 |
Redundancy | 26.6 | 27.7 |
CC(1/2) | 1.000 | 0.363 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | VAPOR DIFFUSION, SITTING DROP | 293 | 0.2 M Ammonium sulfate, 20% w/v PEG 3350 |