7L24

HPK1 IN COMPLEX WITH COMPOUND 11

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SLS BEAMLINE X10SA
Synchrotron site	SLS
Beamline	X10SA
Temperature [K]	100
Detector technology	PIXEL
Collection date	2018-10-24
Detector	DECTRIS PILATUS 6M
Wavelength(s)	1.00001
Spacegroup name	P 1 21 1
Unit cell lengths	77.874, 107.669, 85.971
Unit cell angles	90.00, 107.98, 90.00

Refinement procedure

Resolution	81.770 - 2.680
R-factor	0.2267
Rwork	0.226
R-free	0.27200
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	PREVIOUSLY SOLVED STUCTURE
RMSD bond length	0.010
RMSD bond angle	1.362
Data reduction software	XDS
Data scaling software	XSCALE
Refinement software	REFMAC (5.8.0049)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	81.770	2.930
High resolution limit [Å]	2.680	2.680
Rmeas	0.049	0.561
Number of reflections	37113	8686
<I/σ(I)>	18.54	69.49
Completeness [%]	97.6	98
Redundancy	2.4	2.4
CC(1/2)	0.999	1.000

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION		293	UNDISCLOSED