Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7L1X

Structure of human CK2 alpha kinase (catalytic subunit) with the inhibitor 108600.

Experimental procedure
Experimental methodSINGLE WAVELENGTH
Source typeSYNCHROTRON
Source detailsAPS BEAMLINE 23-ID-D
Synchrotron siteAPS
Beamline23-ID-D
Temperature [K]100
Detector technologyCCD
Collection date2011-06-21
DetectorMAR CCD 165 mm
Wavelength(s)0.98011
Spacegroup nameP 1 21 1
Unit cell lengths58.348, 45.981, 63.683
Unit cell angles90.00, 111.84, 90.00
Refinement procedure
Resolution24.880 - 1.800
R-factor0.1754
Rwork0.173
R-free0.22120
Structure solution methodMOLECULAR REPLACEMENT
Starting model (for MR)3owj
RMSD bond length0.005
RMSD bond angle1.225
Data reduction softwareHKL-2000
Data scaling softwareHKL-2000
Phasing softwarePHASER
Refinement softwareREFMAC (5.8.0267)
Data quality characteristics
 OverallOuter shell
Low resolution limit [Å]25.0001.840
High resolution limit [Å]1.8001.800
Rmerge0.0910.500
Number of reflections282331485
<I/σ(I)>18.51
Completeness [%]97.3
Redundancy3.9
Crystallization Conditions
crystal IDmethodpHtemperaturedetails
1VAPOR DIFFUSION, HANGING DROP7.5293100 mM Tris-HCl pH 7.5 200 mM ammonium sulfate 21% PEG5000

227344

PDB entries from 2024-11-13

PDB statisticsPDBj update infoContact PDBjnumon