7HVP

X-RAY CRYSTALLOGRAPHIC STRUCTURE OF A COMPLEX BETWEEN A SYNTHETIC PROTEASE OF HUMAN IMMUNODEFICIENCY VIRUS 1 AND A SUBSTRATE-BASED HYDROXYETHYLAMINE INHIBITOR

Experimental procedure

Spacegroup name	P 21 21 21
Unit cell lengths	51.200, 58.800, 62.000
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	10.000 - 2.400
R-factor	0.146
RMSD bond length	0.020
RMSD bond angle	0.060
Refinement software	PROFFT

Data quality characteristics

	Overall
High resolution limit [Å]	2.400 *
Rmerge	0.089 *
Number of reflections	5398 *

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	Vapor diffusion, hanging drop *		23 *

Crystallization Reagents in Literatures

ID	crystal ID	solution	reagent name	concentration (unit)	details
1	1	reservoir	ammonium sulfate	55-60 (%(v/v)sat)
2	1	reservoir	sodium acetate	0.1 (M)
3	1	drop	protein	5 (mg/ml)
4	1	drop	dimethyl sulfoxide	9 (%(v/v))