6Y0F
Structure of human FAPalpha in complex with linagliptin
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X06SA |
| Synchrotron site | SLS |
| Beamline | X06SA |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2008-10-01 |
| Detector | DECTRIS PILATUS3 6M |
| Wavelength(s) | 1.000 |
| Spacegroup name | P 1 21 1 |
| Unit cell lengths | 67.586, 253.604, 115.247 |
| Unit cell angles | 90.00, 89.76, 90.00 |
Refinement procedure
| Resolution | 47.930 - 2.924 |
| R-factor | 0.2078 |
| Rwork | 0.207 |
| R-free | 0.24300 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Starting model (for MR) | 1z68 |
| RMSD bond length | 0.007 |
| RMSD bond angle | 0.850 |
| Data reduction software | XDS |
| Data scaling software | XSCALE |
| Phasing software | MOLREP |
| Refinement software | BUSTER (2.11.7 (17-DEC-2019)) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 48.000 | 3.150 |
| High resolution limit [Å] | 2.920 | 2.920 |
| Number of reflections | 81742 | 16579 |
| <I/σ(I)> | 11.8 | |
| Completeness [%] | 98.0 | |
| Redundancy | 2.9 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION | 9 | 293 | 35% (v/v) PEG2000MME, 0.40 M lithium salt |
