6RHY

Structure of pore-forming amyloid-beta tetramers

Spectrometer

Experimental method: SOLUTION NMR

Spectrometer ID	Spectrometer maker	Spectrometer model	Spectrometer type	Spectrometer field strength
1	Bruker	AVANCE III		900
2	Bruker	AVANCE		800

Experiment

experiment id	conditions id	solution id	Experiment type
1	2	1	2D 1H-15N TROSY
10	1	3	3D Hme(Cme[C]CA)NH
11	1	3	3D (H)C-TOCSY-C-TOCSY-(C)H
12	1	4	3D Hm-CmHm NOESY
13	1	4	3D Cm-CmHm NOESY
14	1	4	3D Hm-NH NOESY
15	1	4	3D Cm-NH NOESY
16	1	1	2D 1H-15N TROSY
17	1	2	3D HNCA
18	1	2	3D HNCACB
19	2	2	3D 13C-HMQC-[1H,1H]-NOESY-13C-HMQC
2	2	2	3D HNCA
20	2	4	3D Hm-CmHm NOESY
21	2	4	3D Cm-CmHm NOESY
22	2	4	3D Hm-NH NOESY
23	2	4	3D Cm-NH NOESY
3	1	2	3D HNCO
4	1	2	3D HN(CO)CA
5	2	2	3D HNCACB
6	1	2	3D HN(COCA)CB
7	1	2	3D 13C-HMQC-[1H,1H]-NOESY-13C-HMQC
8	1	3	3D (Hme)Cme([C]CA)CO
9	1	3	3D (Hme)Cme([C]CA)NH

NMR Sample

conditions id	NMR sample pH	NMR sample pressure	NMR sample temperature
1	8.5	1	310.15
2	9.5	1	310.15

Conformers

Conformers Calculated Total Number	500
Conformers Submitted Total Number	15