6O0H
Cryo-EM structure of human ATP-citrate lyase in complex with inhibitor NDI-091143
EM specimen
| Vitrification | Yes |
| Instrument | FEI VITROBOT MARK II |
EM Data Collection
| Microscope | FEI TITAN KRIOS |
| Electron Gun | FIELD EMISSION GUN |
| Accelerating Voltage (kV) | 300 |
| Cs (mm) | 2.7 |
| Detector | GATAN K2 SUMMIT (4k x 4k) |
3D Reconstruction
| Method | SINGLE PARTICLE |
| Resolution (Å) | 3.67 |
| Number of Particle | 250156 |
| Software | Gautomatch,RELION,PHENIX,Leginon,CTFFIND,Coot |
| Symmetry | D2 |
| CTF correction | NONE |
