6NQU

Human LSD1 in complex with GSK2879552

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Synchrotron site	Australian Synchrotron
Beamline	MX1
Temperature [K]	100
Detector technology	CCD
Collection date	2017-02-07
Detector	ADSC QUANTUM 315r
Wavelength(s)	0.9537
Spacegroup name	P 61 2 2
Unit cell lengths	187.478, 187.478, 107.285
Unit cell angles	90.00, 90.00, 120.00

Refinement procedure

Resolution	29.836 - 2.700
R-factor	0.2208
Rwork	0.219
R-free	0.25750
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	2ejr
RMSD bond length	0.004
RMSD bond angle	0.851
Data reduction software	MOSFLM
Data scaling software	Aimless
Phasing software	PHASER
Refinement software	PHENIX ((1.13_2998: ???))

Data quality characteristics

	Overall
Low resolution limit [Å]	29.840
High resolution limit [Å]	2.700
Number of reflections	30804
<I/σ(I)>	10.1
Completeness [%]	99.6
Redundancy	10.8

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP	7	296	PEG3350 6%, 0.1M Ammonium citrate pH7.0