6HWO

Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-1335

Refinement Statistics

Experimental method:X-RAY DIFFRACTION (1.99 Å)

Cell axes98.465110.848160.461
Cell angles90.0090.0090.00
SpacegroupP 21 21 21
Resolution limits80.19 - 1.99
the highest resolution shell value2.040 - 1.989
R-factor0.20108
R-work0.19819
the highest resolution shell value0.364
R-free0.25539
the highest resolution shell value0.407
RMSD bond length0.019
RMSD bond angle1.935

Data Collection Statistics

Resolution limits80.19 - 1.99
the highest resolution shell value -
Number of reflections120894
Rmerge_l_obs0.066
the highest resolution shell value0.790
Completeness100.0
Redundancy6.5
the highest resolution shell value6.6

Crystallization Conditions

crystal IDmethodpHpH rangetemperatureunit
1VAPOR DIFFUSION, HANGING DROP7.5293

Crystallization Reagents

IDcrystal IDsolution IDreagent nameconcentrationdetails
Crystallization Reagents in Literatures*
IDcrystal IDsolutionreagent nameconcentration (unit)details
Annotated Information is extracted from Literature Info*