6RN6
DPP1 in complex with inhibitor
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | ESRF BEAMLINE ID23-2 |
| Synchrotron site | ESRF |
| Beamline | ID23-2 |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Collection date | 2007-07-19 |
| Detector | ADSC QUANTUM 4 |
| Wavelength(s) | 0.8730 |
| Spacegroup name | P 31 2 1 |
| Unit cell lengths | 84.591, 84.591, 223.385 |
| Unit cell angles | 90.00, 90.00, 120.00 |
Refinement procedure
| Resolution | 14.870 - 2.400 |
| R-factor | 0.176 |
| Rwork | 0.174 |
| R-free | 0.22100 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Starting model (for MR) | 1k3b |
| Data reduction software | MOSFLM |
| Data scaling software | SCALA |
| Phasing software | MOLREP |
| Refinement software | BUSTER (2.11.7) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 74.500 | 2.420 |
| High resolution limit [Å] | 2.400 | 2.400 |
| Rmerge | 0.099 | 0.763 |
| Number of reflections | 36889 | 1786 |
| <I/σ(I)> | 11.3 | 2.2 |
| Completeness [%] | 99.5 | 95.6 |
| Redundancy | 3.9 | 3.9 |
| CC(1/2) | 0.996 | 0.704 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, HANGING DROP | 5 | 293 | PEG 3350, 0.2 M Ammoniumsulphate, 0.1 M sodium acetate |
