6RN6
DPP1 in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Dipeptidyl peptidase 1 | polymer | 119 | 13500.2 | 2 | UniProt (P53634) Pfam (PF08773) | Homo sapiens (Human) | Cathepsin C,Cathepsin J,Dipeptidyl peptidase I,DPPI,Dipeptidyl transferase |
| 2 | B, E (B, E) | Dipeptidyl peptidase 1 | polymer | 163 | 18373.7 | 2 | UniProt (P53634) Pfam (PF00112) | Homo sapiens (Human) | Cathepsin C,Cathepsin J,Dipeptidyl peptidase I,DPPI,Dipeptidyl transferase |
| 3 | C, F (C, F) | Dipeptidyl peptidase 1 | polymer | 69 | 7583.4 | 2 | UniProt (P53634) | Homo sapiens (Human) | Cathepsin C,Cathepsin J,Dipeptidyl peptidase I,DPPI,Dipeptidyl transferase |
| 4 | G, H, J (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 5 | I (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | K, L, M, N, P (B, C, E) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 7 | O (E) | (2~{S},4~{R})-~{N}-[(2~{S})-1-azanyl-3-(4-phenylphenyl)propan-2-yl]-4-oxidanyl-pyrrolidine-2-carboxamide | non-polymer | 339.4 | 1 | Chemie (K9Q) | |||
| 8 | Q, R, S, T, U... (A, B, C, D, E...) | water | water | 18.0 | 227 | Chemie (HOH) |
Sequence modifications
B, E: 206 - 367 (UniProt: P53634)
| PDB | External Database | Details |
|---|---|---|
| Ala 205 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 78914.6 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1272.4 | |
| All* | Total formula weight | 80187.0 |
