6PL2
TRK-A IN COMPLEX WITH LIGAND 1a
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X06SA |
| Synchrotron site | SLS |
| Beamline | X06SA |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2015-12-22 |
| Detector | DECTRIS PILATUS 6M-F |
| Wavelength(s) | 1.0 |
| Spacegroup name | P 31 1 2 |
| Unit cell lengths | 52.080, 52.080, 226.964 |
| Unit cell angles | 90.00, 90.00, 120.00 |
Refinement procedure
| Resolution | 45.000 - 2.590 |
| R-factor | 0.20155 |
| Rwork | 0.196 |
| R-free | 0.27414 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.008 |
| RMSD bond angle | 1.226 |
| Data reduction software | XDS |
| Data scaling software | XSCALE |
| Refinement software | REFMAC (5.6.0117) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 75.660 | 2.840 |
| High resolution limit [Å] | 2.590 | 2.590 |
| Rmerge | 0.730 | 0.435 |
| Number of reflections | 11318 | |
| <I/σ(I)> | 17.96 | |
| Completeness [%] | 99.6 | 98.8 |
| Redundancy | 4.7 | 4.5 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, HANGING DROP | 277.15 | 20mM Tris/HCl |
