6O4U
Co-crystal structure of Mcl1 with inhibitor
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | APS BEAMLINE 22-ID |
Synchrotron site | APS |
Beamline | 22-ID |
Temperature [K] | 173 |
Detector technology | CCD |
Collection date | 2009-08-06 |
Detector | MAR CCD 165 mm |
Wavelength(s) | 1.0 |
Spacegroup name | P 1 21 1 |
Unit cell lengths | 36.833, 89.162, 42.721 |
Unit cell angles | 90.00, 106.24, 90.00 |
Refinement procedure
Resolution | 50.000 - 1.700 |
Data reduction software | DENZO |
Data scaling software | SCALEPACK |
Phasing software | AMoRE |
Refinement software | X-PLOR |
Data quality characteristics
Overall | Outer shell | |
Low resolution limit [Å] | 50.000 | 1.760 |
High resolution limit [Å] | 1.700 | 1.700 |
Number of reflections | 29272 | |
<I/σ(I)> | 12.2 | |
Completeness [%] | 99.1 | |
Redundancy | 3.41 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | VAPOR DIFFUSION, HANGING DROP | 8 | 277 | 100 mM Tris pH 8.0, 3% Methanol, 30-42.5% PEG6K |