6JIO

Human LXR-beta in complex with a ligand

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SSRF BEAMLINE BL19U1
Synchrotron site	SSRF
Beamline	BL19U1
Temperature [K]	110
Detector technology	PIXEL
Collection date	2018-12-08
Detector	DECTRIS PILATUS3 S 6M
Wavelength(s)	0.9791
Spacegroup name	P 21 21 21
Unit cell lengths	67.137, 106.888, 150.803
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	50.010 - 2.600
R-factor	0.2635
Rwork	0.262
R-free	0.28478
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	5hjp
RMSD bond length	0.007
RMSD bond angle	1.122
Data reduction software	XDS
Data scaling software	Aimless
Phasing software	MOLREP
Refinement software	REFMAC (5.8.0158)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	50.140	2.720
High resolution limit [Å]	2.600	2.600
Rmerge	0.083
Rmeas		0.296
Number of reflections	34182	4104
<I/σ(I)>	17.8	2.6
Completeness [%]	100.0
Redundancy	9.8

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	EVAPORATION		281	22% PEG 3350, 0.1 M Tris HCl pH 8.5