6EW8
Crystal structure of the BCL6 BTB domain in complex with anilinopyrimidine ligand
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | APS BEAMLINE 17-ID |
| Synchrotron site | APS |
| Beamline | 17-ID |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2015-10-05 |
| Detector | DECTRIS PILATUS3 6M |
| Wavelength(s) | 0.9 |
| Spacegroup name | C 1 2 1 |
| Unit cell lengths | 30.668, 73.017, 53.995 |
| Unit cell angles | 90.00, 104.55, 90.00 |
Refinement procedure
| Resolution | 36.510 - 1.840 |
| R-factor | 0.185 |
| Rwork | 0.182 |
| R-free | 0.24400 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.010 |
| RMSD bond angle | 1.070 |
| Data reduction software | XDS |
| Data scaling software | Aimless |
| Phasing software | PHASER |
| Refinement software | BUSTER (2.11.6) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 36.510 | 1.940 |
| High resolution limit [Å] | 1.840 | 1.840 |
| Number of reflections | 8260 | |
| <I/σ(I)> | 18.9 | 4.4 |
| Completeness [%] | 82.9 | 34.4 |
| Redundancy | 3.3 | 2 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, SITTING DROP | 310 | unknown |
