5VFI
Bruton's tyrosine kinase (BTK) with GDC-0853
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X06SA |
| Synchrotron site | SLS |
| Beamline | X06SA |
| Temperature [K] | 110 |
| Detector technology | PIXEL |
| Collection date | 2010-07-24 |
| Detector | DECTRIS PILATUS 6M |
| Wavelength(s) | 1.00004 |
| Spacegroup name | P 21 21 2 |
| Unit cell lengths | 72.867, 103.908, 38.464 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 59.660 - 1.590 |
| R-factor | 0.18867 |
| Rwork | 0.186 |
| R-free | 0.21576 |
| RMSD bond length | 0.016 |
| RMSD bond angle | 1.906 |
| Data reduction software | XDS |
| Data scaling software | XSCALE |
| Phasing software | REFMAC |
| Refinement software | REFMAC (5.8.0155) |
Data quality characteristics
| Overall | |
| Low resolution limit [Å] | 60.000 |
| High resolution limit [Å] | 1.590 |
| Number of reflections | 40127 |
| <I/σ(I)> | 21.2 |
| Completeness [%] | 100.0 |
| Redundancy | 7.8 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION | 6.5 | 300 | PEG 5000 MME ammonium sulfate MES pH 6.5 |
