5MQK
Crystal structure of CREBBP bromodomain complexed with CBP019
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | SLS BEAMLINE X06SA |
Synchrotron site | SLS |
Beamline | X06SA |
Temperature [K] | 100 |
Detector technology | PIXEL |
Collection date | 2016-09-26 |
Detector | DECTRIS EIGER X 16M |
Wavelength(s) | 0.99998 |
Spacegroup name | H 3 |
Unit cell lengths | 122.356, 122.356, 40.368 |
Unit cell angles | 90.00, 90.00, 120.00 |
Refinement procedure
Resolution | 37.720 - 1.530 |
R-factor | 0.1854 |
Rwork | 0.184 |
R-free | 0.21020 |
Structure solution method | MOLECULAR REPLACEMENT |
RMSD bond length | 0.007 |
RMSD bond angle | 0.915 |
Data reduction software | XDS |
Data scaling software | SCALA |
Phasing software | PHASER |
Refinement software | PHENIX ((1.11.1_2575: ???)) |
Data quality characteristics
Overall | |
Low resolution limit [Å] | 37.720 |
High resolution limit [Å] | 1.530 |
Rmerge | 0.041 |
Number of reflections | 33860 |
<I/σ(I)> | 16.5 |
Completeness [%] | 99.6 |
Redundancy | 5.1 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | VAPOR DIFFUSION, SITTING DROP | 277 | 0.15 M KSCN, 20% PEG3350, 10% EG |