5MPN
Crystal structure of CREBBP bromodomain complexed with FA26
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | SLS BEAMLINE X06SA |
Synchrotron site | SLS |
Beamline | X06SA |
Temperature [K] | 100 |
Detector technology | PIXEL |
Collection date | 2016-11-27 |
Detector | DECTRIS EIGER X 16M |
Wavelength(s) | 1.00001 |
Spacegroup name | P 21 21 21 |
Unit cell lengths | 44.584, 44.723, 60.757 |
Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
Resolution | 36.017 - 1.230 |
R-factor | 0.1587 |
Rwork | 0.158 |
R-free | 0.16740 |
RMSD bond length | 0.014 |
RMSD bond angle | 1.000 |
Data reduction software | XDS |
Data scaling software | SCALA |
Phasing software | PHASER |
Refinement software | PHENIX ((1.11.1_2575: ???)) |
Data quality characteristics
Overall | |
Low resolution limit [Å] | 44.720 |
High resolution limit [Å] | 1.230 |
Rmerge | 0.058 |
Number of reflections | 34316 |
<I/σ(I)> | 16.5 |
Completeness [%] | 95.6 |
Redundancy | 6.8 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | VAPOR DIFFUSION, HANGING DROP | 6.5 | 277 | 0.2 M MgCl2, 0.1 M Bis-Tris, pH6.5, 5% EG, 23% PEG3350 |