5JKG

The crystal structure of FGFR4 kinase domain in complex with LY2874455

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SSRF BEAMLINE BL17U
Synchrotron site	SSRF
Beamline	BL17U
Temperature [K]	100
Detector technology	CCD
Collection date	2015-12-18
Detector	ADSC QUANTUM 315r
Wavelength(s)	0.9789
Spacegroup name	P 43 21 2
Unit cell lengths	61.887, 61.887, 186.059
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	31.891 - 2.352
R-factor	0.2375
Rwork	0.233
R-free	0.27740
RMSD bond length	0.009
RMSD bond angle	1.070
Data reduction software	HKL-3000
Data scaling software	HKL-3000
Phasing software	PHENIX
Refinement software	PHENIX ((1.10_2155: ???))

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	31.891	2.440
High resolution limit [Å]	2.352	2.350
Rmerge	0.079	0.756
Number of reflections	15348
<I/σ(I)>	59.8
Completeness [%]	99.1
Redundancy	14.8

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		277	0.65M NH4H2PO4