5A8Y
Crystal Structure of human neutrophil elastase in complex with a dihydropyrimidone inhibitor
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | ROTATING ANODE |
| Source details | BRUKER X8 PROTEUM |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Detector | BRUKER |
| Spacegroup name | P 63 |
| Unit cell lengths | 73.025, 73.025, 69.842 |
| Unit cell angles | 90.00, 90.00, 120.00 |
Refinement procedure
| Resolution | 36.510 - 1.900 |
| R-factor | 0.16358 |
| Rwork | 0.161 |
| R-free | 0.22131 |
| Structure solution method | OTHER |
| Starting model (for MR) | NONE |
| Data reduction software | SAINT |
| Data scaling software | SADABS |
| Refinement software | REFMAC (5.2.0019) |
Data quality characteristics
| Overall | |
| Low resolution limit [Å] | 36.510 |
| High resolution limit [Å] | 1.900 |
| Rmerge | 0.070 |
| Number of reflections | 16760 |
| <I/σ(I)> | 19.8 |
| Completeness [%] | 99.9 |
| Redundancy | 9.18 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 |
