4XT9

RORgamma (263-509) complexed with GSK2435341A and SRC2

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SSRF BEAMLINE BL17U
Synchrotron site	SSRF
Beamline	BL17U
Temperature [K]	100
Detector technology	CCD
Collection date	2010-10-20
Detector	ADSC QUANTUM 210r
Wavelength(s)	1.0
Spacegroup name	P 41 21 2
Unit cell lengths	62.000, 62.000, 154.700
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	57.580 - 2.250
R-factor	0.21569
Rwork	0.214
R-free	0.24489
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	3l0j
RMSD bond length	0.007
RMSD bond angle	1.008
Data scaling software	HKL-2000
Phasing software	PHASER
Refinement software	REFMAC (5.5.0102)

Data quality characteristics

	Overall
Low resolution limit [Å]	57.580
High resolution limit [Å]	2.250
Number of reflections	14291
<I/σ(I)>	22.2
Completeness [%]	99.8
Redundancy	7.5

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		296	0.2M Ammonium Sulfate, 0.1M Bis-Tris, pH 6.5, 14% (w/v) PEG 8000