4G5J

Crystal structure of EGFR kinase in complex with BIBW2992

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SLS BEAMLINE X06SA
Synchrotron site	SLS
Beamline	X06SA
Temperature [K]	100
Detector technology	CCD
Detector	MARMOSAIC 225 mm CCD
Wavelength(s)	1.000
Spacegroup name	I 2 3
Unit cell lengths	144.468, 144.468, 144.468
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	? - 2.800
R-factor	0.2081
Rwork	0.205
R-free	0.25900
RMSD bond length	0.008
RMSD bond angle	1.170
Data reduction software	XDS
Data scaling software	XSCALE
Refinement software	REFMAC (5.2.0005)

Data quality characteristics

	Overall
Low resolution limit [Å]	45.685
High resolution limit [Å]	2.800
Number of reflections	12030
Completeness [%]	96.0

Crystallization Conditions

crystal ID	method	pH	temperature	details
1